COVID-19 Delta variant may evade vaccine immunity

COVID-19 Delta variant may have increased ability to evade vaccine-induced immunity: Study

सम्बन्धित सामग्री

All about Omicron variant of COVID-19

People around the world are concerned about the Omicron variant of COVID-19. Here are the latest expert information about this new variant. What is the Omicron variant?  The Omicron variant of COVID-19 has been called a variant of concern by WHO based on the evidence that it has several mutations that may have an impact on how it behaves. There is still substantial uncertainty regarding Omicron and a lot of research underway to evaluate its transmissibility, severity and reinfection risk. How did the Omicron variant develop?  When a virus is circulating widely and causing numerous infections, the likelihood of the virus mutating increases. The more opportunities a virus has to spread, the more opportunities it has to undergo changes. New variants like Omicron are a reminder that the COVID-19 pandemic is far from over. It is therefore essential that people get the vaccine when available to them and continue to follow existing advice on preventing the spread of the virus, including physical distancing, wearing masks, regular handwashing and keeping indoor areas well ventilated. It is also crucial that vaccines and other public health measures are accessible everywhere. Vaccine inequity leaves lower income countries – many of them in Africa – at the mercy of COVID-19. Well-supplied countries must urgently deliver the doses they promised. Where is the Omicron variant present?  The Omicron variant has now been detected in many countries around the world. WHO reports that Omicron is probably in most countries, even if it hasn’t been detected yet. Is the Omicron variant more severe than other COVID-19 variants?  Early findings suggest that Omicron might be less severe than the Delta variant, but more data is needed and WHO warns that it should not be dismissed as “mild”. Studies are ongoing and this information will be updated as it becomes available.  It is important to remember that all variants of COVID-19 can cause severe disease or death, including the Delta variant that is still dominant worldwide, which is why preventing the spread of the virus and reducing your risk of exposure to the virus is so important. Is the Omicron variant more contagious?  Omicron is spreading more quickly than other variants. Based on the information available, WHO believes it is likely that Omicron will outpace the Delta variant where there is COVID-19 transmission in the community.  However, being vaccinated and taking precautions such as avoiding crowded spaces, keeping your distance from others and wearing a mask are critical in helping to prevent the spread of COVID-19, and we know these actions have been effective against other variants.   Does the Omicron variant cause different symptoms?   There is no information to suggest that Omicron causes different COVID-19 symptoms from other COVID-19 variants. Are the COVID-19 vaccines effective against the Omicron variant?   Researchers are looking into any potential impact the Omicron variant has on the effectiveness of COVID-19 vaccines. Information is still limited, but there may be a small reduction in the effectiveness of vaccines against severe illness and death, and a decline in preventing mild disease and infection. However, WHO reports that so far it looks like the currently available vaccines offer significant protection against severe disease and death. It is also important to be vaccinated to protect against the other widely circulating variants, such as the Delta one. When it’s your turn, make sure to get vaccinated. If your vaccination involves two doses, it’s important to receive both in order to have the maximum protection.   Is a prior COVID-19 infection effective against the Omicron variant? WHO reports that early evidence suggests that previous infection could offer less protection against Omicron in comparison to other variants of concern, such as Delta. Information is still limited though and we will share updates as it becomes available. You should get vaccinated even if you’ve previously had COVID-19. While people who recover from COVID-19 may develop some natural immunity to the virus, we do not yet know how long it lasts or how well you are protected. Vaccines offer more reliable protection. Do current COVID-19 tests detect the Omicron variant?  The widely used PCR and antigen-based rapid diagnostic tests continue to detect infection of COVID-19, including Omicron. Are children more likely to contract the Omicron variant?  Research is ongoing into Omicron’s transmissibility and we will update as more information becomes available. However, people who are mixing socially and those who are unvaccinated are more susceptible to contracting COVID-19. How can I protect myself and my family against the Omicron variant? The most important thing you can do is reduce your risk of exposure to the virus. To protect yourself and your loved ones, make sure to:  Wear a mask that covers your nose and mouth. Make sure that your hands are clean when you put on and remove your mask. Keep a physical distance of at least 1 metre from others.  Avoid poorly ventilated or crowded spaces. Open windows to improve ventilation indoors. Wash your hands regularly.   When it’s your turn, get vaccinated. WHO-approved COVID-19 vaccines are safe and effective.   How can I talk to my child about the Omicron and other COVID-19 variants? News about COVID-19 and now the Omicron variant is flooding our daily lives and it is only natural that curious young children will have questions – lots of them. Here are some pointers to keep in mind tips for helping to explain what can be a complicated topic in simple and reassuring terms.  Children have a right to know what is going on, but it should be explained to them in an age-appropriate way.  Invite your child to share what they have heard and listen to their responses. It is important to be fully engaged and take any fears they have seriously. Be patient, the pandemic and misinformation has caused a lot of worry and uncertainty for everyone. Make sure that you are up to date on the latest information yourself. Websites of international organizations like UNICEF and the World Health Organization are great sources of information about the pandemic. If you don’t know the answer, don’t guess. Use it as an opportunity to explore the answers together.  Remember that kids take their emotional cues from adults, so even if you are worried for your little one knowing that they might be uncomfortable, try not to overshare your fears with your child.  This article was published by UNICEF

COVID-19 Delta variant may evade vaccine immunity

COVID-19 Delta variant may have increased ability to evade vaccine-induced immunity: Study

3rd COVID-19 vaccine dose boosts immunity tenfold: Israeli study

JERUSALEM, September 17: The third vaccine dose against COVID-19 increases the immune protection from infection tenfold, the Israeli Ministry of Health said on Thursday. The ministry said that a new Israeli study, published in the New England Journal of Medicine, examined the effectiveness of the third dose among those over the age of 60, who received the booster shot in August. The tenfold protection is compared to those who received only two doses at least five months ago. The study was conducted by a team of multidisciplinary researchers from the health ministry, the Weizmann Institute of Science, the Hebrew University of Jerusalem, the Technion, the Sheba Medical Center and the KI Research Institute, it said. "The data from Israel indicate high efficacy of Pfizer's third booster dose in preventing COVID-19 infection and serious illness," the ministry noted. Israel began vaccinating its population with the third vaccine dose on Aug. 1, as the Delta variant was spreading in the country and the effectiveness of the first two doses eroded. To date, nearly 3 million Israelis have received the third jab. The researchers found that 12 days after receiving the third shot, the rate of infections was more than 10 times lower among those who received the booster shot than those did not. This means that if the chance of those vaccinated with two doses to get infected with the Delta variant is about 50 percent compared to the unvaccinated, a booster dose lowers the risk to 5 percent, or raises the immune defense to 95 percent, the researchers concluded.

COVID-19 Vaccine Booster Shots

A vast majority of the population of Nepal is yet to receive a full dose of COVID-19 vaccines. However, a debate has already started on whether those who received both doses of the vaccines need a booster dose. At the same time, the rapid spread of the Delta variant throughout the world and increasing reports of breakthrough COVID-19 cases are raising questions either fully vaccinated people should receive an additional booster dose to enhance their immunity.

Pfizer Covid jab declines faster than AstraZeneca: study

Aug 19: The effectiveness of the Pfizer-BioNTech vaccine against Covid-19 declines faster than that of the AstraZeneca jab, according to a new study published on Thursday. "Two doses of Pfizer-BioNTech have greater initial effectiveness against new COVID-19 infections, but this declines faster compared with two doses of Oxford-AstraZeneca," researchers at Oxford University said. The study, which has not been peer reviewed, is based on the results of a survey by Britain's Office for National Statistics that carried out PCR tests from December last year to this month on randomly selected households. It found that "the dynamics of immunity following second doses differed significantly" between Pfizer and AstraZeneca, according to the university's Nuffield Department of Medicine. Pfizer had "greater initial effectiveness" but saw "faster declines in protection against high viral burden and symptomatic infection", when looking at a period of several months after full vaccination, although rates remained low for both jabs. "Results suggest that after four to five months effectiveness of these two vaccines would be similar," the scientists added, while stressing that long-term effects need to be studied. The study's findings come as Israel is administering booster shots, after giving 58 percent of the population two shots of the Pfizer jab. The United States is also set to offer booster vaccines to boost antibody levels following concerns over declining effectiveness of the Pfizer and Moderna vaccines. The Oxford research also found that protection was higher among those who had already been infected with the virus. The study examined two groups of more than 300,000 people over 18, first during the period dominated by the Alpha variant, which emerged in Kent, southeast England, and secondly from May 2021 onwards, when the Delta variant has been dominant.  It confirmed that vaccines are less effective against Delta, which was first seen in India. The AstraZeneca vaccine is the most widely offered in the UK, while those under 40 are offered Pfizer or Moderna due to blood clotting concerns.